Variant · Snv
SIRT2 NM_012237.4(SIRT2):c.132A>T (p.Leu44Phe)
CI-VAR-00126740Explore in graph →p.Leu44PheNM_012237.4:c.132A>TClinVar 775117 rs45535036
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 775117 | Benign | criteria provided, multiple submitters, no conflicts | 2 | Colon adenocarcinoma; Colorectal cancer; Sarcoma; Gastric cancer; Ovarian serous cystadenocarcinoma; Cholangiocarcinoma; Acute myeloid leukemia; Hepatocellular carcinoma; Malignant tumor of esophagus; Uterine corpus endometrial carcinoma; Uterine carcinosarcoma; Thyroid cancer, nonmedullary, 1; Lung cancer; Clear cell carcinoma of kidney; Thymoma; Melanoma; Nonpapillary renal cell carcinoma; Cervical cancer | germline | 3 | Dec 31, 2019 | clinvar |