Variant · Snv
CPSF4 NM_006693.4(CPSF4):c.483G>A (p.Ser161=)
CI-VAR-00126469Explore in graph →p.Ser161=NM_006693.4:c.483G>AClinVar 769333 rs35303224
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 769333 | Benign | criteria provided, multiple submitters, no conflicts | 2 | Colon adenocarcinoma; Sarcoma; Gastric cancer; Lymphoma; Ovarian cancer; Uterine corpus endometrial carcinoma; Cholangiocarcinoma; Acute myeloid leukemia; Hepatocellular carcinoma; Malignant tumor of esophagus; Chronic lymphocytic leukemia/small lymphocytic lymphoma; Uveal melanoma; Thymoma; Melanoma; Nonpapillary renal cell carcinoma; Lung cancer; Clear cell carcinoma of kidney; Familial pancreatic carcinoma; Ovarian serous cystadenocarcinoma; Thyroid cancer, nonmedullary, 1; Adrenocortical carcinoma, hereditary; Cervical cancer | germline | 3 | Jan 15, 2018 | clinvar |