Variant · Snv
BRAP NM_006768.5(BRAP):c.1353G>A (p.Lys451=)
CI-VAR-00126561Explore in graph →p.Lys451=NM_006768.5:c.1353G>AClinVar 768584 rs61739319
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 768584 | Benign | criteria provided, multiple submitters, no conflicts | 2 | Clear cell carcinoma of kidney; Gastric cancer; Ovarian serous cystadenocarcinoma; Malignant tumor of esophagus; Uterine corpus endometrial carcinoma; Cervical cancer | germline | 3 | May 08, 2018 | clinvar |