Variant · Snv
UCP3 NM_003356.4(UCP3):c.824+1G>A
CI-VAR-00005710Explore in graph →NM_003356.4:c.824+1G>AClinVar 7578 rs45476292
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 7578 | Benign | criteria provided, multiple submitters, no conflicts | 2 | UCP3 POLYMORPHISM, EXON 6 SPLICE DONOR JUNCTION; Morbid obesity; UCP3-related disorder; Uterine corpus endometrial carcinoma; Sarcoma; Uterine carcinosarcoma; Adrenocortical carcinoma, hereditary; Cervical cancer; Thymoma; Thyroid cancer, nonmedullary, 1; Melanoma; Acute myeloid leukemia; Hepatocellular carcinoma; Clear cell carcinoma of kidney; Ovarian serous cystadenocarcinoma; Malignant tumor of esophagus; Lung cancer | germline | 7 | Feb 04, 2026 | clinvar |