LRBA NM_001364905.1(LRBA):c.4100A>G (p.Asn1367Ser)

CI-VAR-00128742Explore in graph →p.Asn1367SerNM_001364905.1:c.4100A>GClinVar 742708 rs138220755

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
742708	Conflicting classifications of pathogenicity	criteria provided, conflicting classifications	1	Combined immunodeficiency due to LRBA deficiency; Inborn genetic diseases; Acute myeloid leukemia	germline	4	Jan 04, 2026	clinvar