Variant · Snv
PLOD2 NM_182943.3(PLOD2):c.1126A>C (p.Met376Leu)
CI-VAR-00128726Explore in graph →p.Met376LeuNM_182943.3:c.1126A>CClinVar 737604 rs140613062
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-06
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260908-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 737604 | Conflicting classifications of pathogenicity | criteria provided, conflicting classifications | 1 | Ovarian serous cystadenocarcinoma; Hepatocellular carcinoma; Malignant tumor of esophagus; Familial cancer of breast; Clear cell carcinoma of kidney | germline | 3 | Jan 28, 2026 | clinvar |