Variant · Snv
TNS2 NM_170754.4(TNS2):c.1086C>T (p.Gly362=)
CI-VAR-00128259Explore in graph →p.Gly362=NM_170754.4:c.1086C>TClinVar 732869 rs151036307
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 732869 | Benign | criteria provided, single submitter | 1 | TNS2-related disorder; Clear cell carcinoma of kidney; Colorectal cancer; Ovarian serous cystadenocarcinoma; Colon adenocarcinoma; Sarcoma; Melanoma; Familial cancer of breast; Malignant tumor of urinary bladder; Hepatocellular carcinoma; Malignant tumor of esophagus; Cervical cancer | germline | 3 | Sep 30, 2025 | clinvar |