SDHC NM_003001.5(SDHC):c.405+1G>A

CI-VAR-00005671Explore in graph →NM_003001.5:c.405+1G>AClinVar 7244 rs587776653

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
7244	Pathogenic	criteria provided, multiple submitters, no conflicts	2	Carney-Stratakis syndrome; Gastrointestinal stromal tumor; Carney triad; Hereditary pheochromocytoma and paraganglioma; Pheochromocytoma/paraganglioma syndrome 3; Hereditary cancer-predisposing syndrome; SDHC-related disorder	germline	6	Apr 01, 2025	clinvar