Variant · Snv
MIIP NM_021933.4(MIIP):c.840C>G (p.His280Gln)
CI-VAR-00127342Explore in graph →p.His280GlnNM_021933.4:c.840C>GClinVar 717888 rs117146839
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 717888 | Benign | criteria provided, single submitter | 1 | Thyroid cancer, nonmedullary, 1; Hepatocellular carcinoma; Malignant lymphoma, large B-cell, diffuse; Colon adenocarcinoma; Gastric cancer; Ovarian serous cystadenocarcinoma; Malignant tumor of urinary bladder; Malignant tumor of esophagus; Cervical cancer | germline | 2 | May 08, 2018 | clinvar |