Variant · Snv
MDH2 NM_005918.4(MDH2):c.555G>A (p.Lys185=)
CI-VAR-00127526Explore in graph →p.Lys185=NM_005918.4:c.555G>AClinVar 711986 rs142812282
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-06
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260908-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 711986 | Benign | criteria provided, multiple submitters, no conflicts | 2 | Uterine corpus endometrial carcinoma; Malignant lymphoma, large B-cell, diffuse; Nonpapillary renal cell carcinoma; Cervical cancer; Clear cell carcinoma of kidney; Lung cancer; Colon adenocarcinoma; Sarcoma; Thyroid cancer, nonmedullary, 1; Malignant tumor of esophagus | germline | 5 | Feb 03, 2026 | clinvar |