Variant · Snv
MYOF NM_013451.4(MYOF):c.2114C>T (p.Thr705Met)
CI-VAR-00127593Explore in graph →p.Thr705MetNM_013451.4:c.2114C>TClinVar 710747 rs150897152
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-24
- Retrieved
- Sep 29, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260929-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 710747 | Likely benign | criteria provided, multiple submitters, no conflicts | 2 | MYOF-related disorder; Uterine carcinosarcoma; Thymoma; Melanoma; Acute myeloid leukemia; Colorectal cancer; Gastric cancer; Malignant tumor of esophagus; Familial cancer of breast; Clear cell carcinoma of kidney; Colon adenocarcinoma; Sarcoma; Lung cancer | germline | 5 | Nov 26, 2024 | clinvar |