Variant · Snv
KLF8 NM_007250.5(KLF8):c.646+5G>A
CI-VAR-00128028Explore in graph →NM_007250.5:c.646+5G>AClinVar 710494 rs189635205
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-24
- Retrieved
- Sep 29, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260929-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 710494 | Benign/Likely benign | criteria provided, multiple submitters, no conflicts | 2 | Papillary renal cell carcinoma type 1; Thyroid cancer, nonmedullary, 1; Acute myeloid leukemia; Malignant tumor of urinary bladder; Chronic lymphocytic leukemia/small lymphocytic lymphoma; Sarcoma; Ovarian serous cystadenocarcinoma; Lung cancer; Familial cancer of breast; Familial pancreatic carcinoma; Gastric cancer; Cervical cancer | germline | 4 | Nov 28, 2024 | clinvar |