Variant · Snv
ITGA4 NM_000885.6(ITGA4):c.1900T>A (p.Ser634Thr)
CI-VAR-00127391Explore in graph →p.Ser634ThrNM_000885.6:c.1900T>AClinVar 709073 rs35322532
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-06
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260908-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 709073 | Benign | criteria provided, multiple submitters, no conflicts | 2 | ITGA4-related disorder; Uterine corpus endometrial carcinoma; Lung cancer; Clear cell carcinoma of kidney; Malignant tumor of esophagus; Sarcoma; Gastric cancer; Acute myeloid leukemia; Hepatocellular carcinoma | germline | 4 | Aug 20, 2018 | clinvar |