ARHGEF18 NM_001367823.1(ARHGEF18):c.1699C>G (p.Leu567Val) — variant · CancerIndex

Variant · Snv

ARHGEF18 NM_001367823.1(ARHGEF18):c.1699C>G (p.Leu567Val)

CI-VAR-00127787Explore in graph →p.Leu567ValNM_001367823.1:c.1699C>GClinVar 708729 rs140297736

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
708729	Likely benign	criteria provided, multiple submitters, no conflicts	2	Acute myeloid leukemia; Malignant tumor of esophagus; Lung cancer; Cervical cancer; Ovarian serous cystadenocarcinoma; Melanoma; Gastric cancer; Thyroid cancer, nonmedullary, 1; Clear cell carcinoma of kidney; Uveal melanoma; Sarcoma	germline	4	Jan 26, 2026	clinvar