SDHD NM_003002.4(SDHD):c.149A>G (p.His50Arg)

CI-VAR-00005641Explore in graph →p.His50ArgNM_003002.4:c.149A>GClinVar 6909 rs11214077

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
6909	Benign/Likely benign	criteria provided, multiple submitters, no conflicts	2	Carcinoid tumor of intestine; Hereditary cancer-predisposing syndrome; Pheochromocytoma/paraganglioma syndrome 1; Carney-Stratakis syndrome; Cowden syndrome 3; Pheochromocytoma; Paragangliomas with sensorineural hearing loss; SDHD-related disorder; Hereditary pheochromocytoma and paraganglioma; Mitochondrial complex 2 deficiency, nuclear type 3	germline	28	Jun 01, 2026	clinvar