PALB2 NM_024675.4(PALB2):c.1084_1085del (p.Thr361_Leu362insTer) — variant · CancerIndex

Variant · Other

PALB2 NM_024675.4(PALB2):c.1084_1085del (p.Thr361_Leu362insTer)

CI-VAR-00119393Explore in graph →p.Thr361_Leu362insTerNM_024675.4:c.1084_1085delClinVar 661924 rs1597097182

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
661924	Pathogenic	criteria provided, multiple submitters, no conflicts	2	Familial cancer of breast; Hereditary cancer-predisposing syndrome; Hereditary breast ovarian cancer syndrome	germline	4	Jan 21, 2026	clinvar