Variant · Indel
NR0B2 NM_021969.3(NR0B2):c.293_301delinsAC (p.Leu98fs)
CI-VAR-00113721Explore in graph →p.Leu98fsNM_021969.3:c.293_301delinsACClinVar 636298 rs1570714352
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-06
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260908-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 636298 | Likely pathogenic | criteria provided, single submitter | 1 | APC-mutation negative familial colorectal cancer; Obesity | germline | 2 | Aug 12, 2021 | clinvar |