Variant · Snv
ZGRF1 NM_018392.5(ZGRF1):c.142C>A (p.Leu48Met)
CI-VAR-00109850Explore in graph →p.Leu48MetNM_018392.5:c.142C>AClinVar 617844 rs61745597
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-06
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260908-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 617844 | Benign/Likely benign | criteria provided, multiple submitters, no conflicts | 2 | Childhood apraxia of speech; Autism spectrum disorder; Thyroid cancer, nonmedullary, 1; Acute myeloid leukemia; Hepatocellular carcinoma; Nonpapillary renal cell carcinoma; Thymoma; Adrenocortical carcinoma, hereditary; Cervical cancer; Lung cancer | germline | 5 | Apr 17, 2023 | clinvar |