PIGT NM_015937.6(PIGT):c.494-2A>G

CI-VAR-00108842Explore in graph →NM_015937.6:c.494-2A>GClinVar 583283 rs200790673

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
583283	Pathogenic	criteria provided, multiple submitters, no conflicts	2	Multiple congenital anomalies-hypotonia-seizures syndrome 3; Malignant tumor of urinary bladder; PIGT-related disorder	germline	10	Apr 20, 2026	clinvar