Variant · Deletion
RNASEH2B NM_024570.4(RNASEH2B):c.136+1del
CI-VAR-00105960Explore in graph →NM_024570.4:c.136+1delClinVar 566198 rs75186889
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 566198 | Pathogenic | criteria provided, multiple submitters, no conflicts | 2 | Aicardi-Goutieres syndrome 2; RNASEH2B-related disorder; Aicardi Goutieres syndrome; Papillary renal cell carcinoma type 1 | germline | 8 | Apr 29, 2026 | clinvar |