KIAA0586 NM_001329943.3(KIAA0586):c.974A>T (p.Glu325Val)

CI-VAR-00098295Explore in graph →p.Glu325ValNM_001329943.3:c.974A>TClinVar 542191 rs144456198

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
542191	Benign/Likely benign	criteria provided, multiple submitters, no conflicts	2	Joubert syndrome 23; Short-rib thoracic dysplasia 14 with polydactyly; Inborn genetic diseases; KIAA0586-related disorder; Clear cell carcinoma of kidney; Malignant lymphoma, large B-cell, diffuse; Cervical cancer; Gastric cancer	germline	8	Apr 01, 2026	clinvar