KCNQ1 NM_000218.3(KCNQ1):c.868G>A (p.Glu290Lys)

CI-VAR-00012063Explore in graph →p.Glu290LysNM_000218.3:c.868G>AClinVar 53120 rs199473464

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
53120	Uncertain significance	criteria provided, multiple submitters, no conflicts	2	Congenital long QT syndrome; Long QT syndrome 1; Short QT syndrome type 2; Atrial fibrillation, familial, 3; Jervell and Lange-Nielsen syndrome 1; Cardiac arrhythmia; Long QT syndrome; Beckwith-Wiedemann syndrome; Cardiovascular phenotype; Uterine carcinosarcoma	germline	10	Feb 25, 2026	clinvar