Variant · Snv
VPS53 NM_001128159.3(VPS53):c.1148A>G (p.Asn383Ser)
CI-VAR-00094171Explore in graph →p.Asn383SerNM_001128159.3:c.1148A>GClinVar 516685 rs79657649
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 516685 | Benign | criteria provided, multiple submitters, no conflicts | 2 | Acute myeloid leukemia; Hepatocellular carcinoma; Malignant tumor of esophagus; Nonpapillary renal cell carcinoma; Uterine corpus endometrial carcinoma; Malignant lymphoma, large B-cell, diffuse; Colon adenocarcinoma; Sarcoma; Gastric cancer; Thyroid cancer, nonmedullary, 1; Familial cancer of breast; Ovarian serous cystadenocarcinoma; Melanoma; Lung cancer | germline | 4 | Feb 04, 2026 | clinvar |