SYNE1 NM_182961.4(SYNE1):c.16409A>G (p.Asp5470Gly)

CI-VAR-00093008Explore in graph →p.Asp5470GlyNM_182961.4:c.16409A>GClinVar 501297 rs747824937

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
501297	Uncertain significance	criteria provided, multiple submitters, no conflicts	2	Emery-Dreifuss muscular dystrophy 4, autosomal dominant; Autosomal recessive ataxia, Beauce type; Gastric cancer	germline	5	Sep 05, 2025	clinvar