Variant · Snv
TBXAS1 NM_001061.7(TBXAS1):c.357G>A (p.Ser119=)
CI-VAR-00092985Explore in graph →p.Ser119=NM_001061.7:c.357G>AClinVar 499773 rs41275018
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 499773 | Benign/Likely benign | criteria provided, multiple submitters, no conflicts | 2 | TBXAS1-related disorder; Clear cell carcinoma of kidney; Colon adenocarcinoma; Sarcoma; Thymoma; Lung cancer; Uterine corpus endometrial carcinoma; Malignant tumor of esophagus; Cervical cancer | germline | 7 | Jan 27, 2026 | clinvar |