Variant · Snv
ZFHX3 NM_006885.4(ZFHX3):c.6156G>A (p.Pro2052=)
CI-VAR-00092527Explore in graph →p.Pro2052=NM_006885.4:c.6156G>AClinVar 493190 rs148383343
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-06
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260908-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 493190 | Conflicting classifications of pathogenicity | criteria provided, conflicting classifications | 1 | ZFHX3-related disorder; Cholangiocarcinoma; Lung cancer; Clear cell carcinoma of kidney; Colon adenocarcinoma; Thyroid cancer, nonmedullary, 1; Melanoma; Acute myeloid leukemia | germline | 4 | Mar 01, 2026 | clinvar |