SCN5A NM_000335.5(SCN5A):c.1141-3C>A

CI-VAR-00008764Explore in graph →NM_000335.5:c.1141-3C>AClinVar 48280 rs41312433

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
48280	Benign/Likely benign	criteria provided, multiple submitters, no conflicts	2	Cardiovascular phenotype; Long QT syndrome 3; Dilated cardiomyopathy 1E; Progressive familial heart block, type 1A; Sick sinus syndrome 1; Ventricular fibrillation, paroxysmal familial, type 1; Brugada syndrome 1; Cardiac arrhythmia; Primary dilated cardiomyopathy; Familial pancreatic carcinoma	germline	21	Feb 04, 2026	clinvar