Variant · Insertion

RAD51D NC_000017.11:g.35115774_35124430dup

CI-VAR-00410187Explore in graph →ClinVar 4820156

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
4820156	Pathogenic	criteria provided, single submitter	1	Breast-ovarian cancer, familial, susceptibility to, 4	germline	1	Dec 07, 2021	clinvar

Nomenclature

Record

Gene: RAD51D
Type: Insertion
HGVS g.: NC_000017.11:g.35115774_35124430dup
Assembly: GRCh38
Position: chr17:35115739
Ref / Alt: A → ACGCACCTGTAGTCCCAGCTACTCGGGAGGCTGAGTCAGGAGAATCACTTGAACCCTGGAGGCGGAGGTTGCAGTGAGCCGAGATCACGCCACTGCACTCCAGCCTGGCAACAGAGTGAAACTCCGTCAAAAAAAAGAAAGAAAGAAGGAAAGAAGGAAAGGAAGGAAGGAAGGAAGGAAGGAAGGAAGGAAGGAAGGAAGAAAGAAAAGGAAGAAAGGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGGCTAGAAACCTGGTGAGTCAGCTTTGATTCTTCACAATACATTCCAAACTCCGACAAAAAAAAAAAAGAAAGAAAGAAAGAAAGGCTAGAAACCTGGTGAGTCAGCTTTGATTCTTCACAATACATTCCTCCTGGTAGTAGGTCTTGTCACAGTTCCTCTTCAACATGTCTCCCACTGTTCTAGACTGGACTCACATACCCCAGGCCAGCACTGCCAGGGCCCTGCTTGGCCTCTGCCACCCTTCCACCCTGCACACCTCTACCCCACTGTCTATAACCCTGCTTTCACAATGGCCTCCCGCCTCCAGGGAGACAGCCGGGCAGATGAGTTAAGAGCCGCGTTCTTAGACTTAGGAGTGTGACAAGCATGAACTCAAATAACTGGTCTGCCGTTTGCTAACTGCACAATCTTGAACAAGTCATTTAACCTGAGTCCCAATTTCTTCACCTATAGAATGATGATTTATTTTTATTTTATTTTATTTTATTTTATTTTTTTGAGATGGAGTCTTGCCCTGTTGCCCAGGCTGGAGTGCAGTGGTGCGATCTCCGCTCACTGCAAGCTCCGCTTCCCGGGTTCATGCTATTCTCCTGCCTCAGCCTTCCGAGTAGCTGGGACTACAGGCGCCCGCCACCACGCCCAGCTAATATTTTGTACTTTTAGTAGAGACGGGGTTTTACCGTGTTAGCCAGGACAGTCTCGATTTCCTGACCTCATGATCCGCCCACCTCAGCCTCCCAAAGTGCTGTGATCACAGGCGTGAGCCACTGCGCCCGGCCTAGAATGATGATTTAAACAGTAACATGCTCATTGGTGGTTGTGACGAATAAATGAAATAATGTACCGTGAAGTGCTGACCGCAGTGCCTCGTTCATCGAAAGCATTCAGCGAAAGTCCATCTGTTCCTCCATGCCCAAGTCCTGCCTTCTTCAGAGCATTCCTGACCCCACTCCACGATCTCCCTGCGGGGACCTGAGGCAGCTGCAGTCCTCCCAGGTTCCCACTTGAGTGCGCCCTCCATGTCTGTTGGATTTATAAACTCCCTAAGCCCAAGGCCAATCGGCTTCCTGTTCACCACTCCCTCCTTACCGTTGCCTCCCTCGGTGCTTACAGCTCTCTTGTATTCACTTGATTTTCCCCTACACCCAACTAGAGGCCTTAAGGGCAGGGGCCTTGCCTCATTCGTGTATGTATCATCTGCACATACCAAGCACCCAGCAGGCCCTTAGCCAGTGCTTGATGGATCACAGACTCAGACCCCCAACCAGGGAAAGCAAGCACCACACTGCATGAACCCTGCCAAGAGAATGTGTTAAGGAAACAGAAAGGGCCACACCAATCCAAAGACCTTTATGGTGGCAGTTATTCATCAATTTCTGAACAAACAGACCAGGAAAAAGGTCAAGACTCACTTGGCCAGCAAACGTCTGTCGTCTTTGCAACTCTTCCCCAACCCACCAAACAACGTGGCGGGACATAACTGCTCCTTTTTTTTGAGAGAGTCTCGCTCTGCCACCAAGGCTGGAGTGCAGTGGTGCGATCTTGGCCTACTGCAACCTCCACCTCCCACATTCAAGCAATTCTCCTGCTGCAGCCTCCCAAGTAGCTGGGACTACAGGCGCCCGCCACCACGCCCGACTAATTTTTGTATGTTTAGTAGAGACGGGGTTTCATCATTTTGGGCGGGCAAGCAGGCCAGGCAGGTCTCAAACTCCCGGCCTCCAGTGATCTGCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGTATGAGCACTGCATCTGGACCGCAACTCCTTCTTTCTCTGAACTCTCCTGTTCTCTACTGCTGCAGATGTGGTGAATAAGTTCTGGGCCACATACTCCCGCGCTTGAGCCTCACCTTTGCCACTTGCTCCTCTTAGGCTAAACTCAAGTAGGGTTAATTATCTCTAACTGGTAGAGTCACTGAAGAGATTACCTAGAACATACAGGTAATGCCTGCACATAGTAGGCACTCAGTAAATGTTCTCTCTTGCCATATCCTTAAGTAAAATAAGAAGTAGGGCCAGAGAAGATGGTGAAAATAATGAGATACTGACAGCTTGTGTTATAGGACAATGCTTCTCAACCAGAGGCAATTGTGCCTCCCAGGGGACATTTAGCCATGTCAGGAGACATTTTTGATGGTTACAACTGGAGCAGGGCTGGTGCTACTGGCATCTAGTGGGCAGAGGCCAGAGATGCTGCTAAACATCCTACACTGCACAGGACAGCCTCCACCCCCCAACAAATAATTACCTGTCCCTAAATATCAATAGTGCCAAGGCTGAGATACCCCATAACCCTGTTATAGGATAAGAATTCAGATGTCCTGACCCCTTTCCTTCCCATCCATTATTGGTTAAAAAAAAAACCCCTCCCGTCTAGACTCAAGCATCAAAAGCAGAGCTGAGAGGAGGCCCCATCCTCCTGCCTCTCTCCTTCTTCCCCAAGTACACACACAAACCTGCCAATGCCAGTGGACAGGATGGCAGTGGAGGTCTTCAGTTCCTCGTAGAGATCAGCGCCATTCACGGGGAAAGCCGAGAACTGAGCCAGCAGCACCCGCCTCAGGGCAACCAGGGCCTGCCAAAGGGCCCCAGACTGCTCAGCAACAAATTGCCCGTAGAAGCTGGCATCCCAGGGTGTCATTCACCCTACTTCTCAATATCTGAGAACCCTCTGCTCCCTTTGGCTTGGGATGGACTTTTGTTATTGTTGTTGTTTCAGACAGGGTCTCACTCTGTCGCCCAGATTGGAGTGCAGTAGCACGATCTCGGCTCACTGCAACCTCTGCCTCCCGGGCTCAAATGATTCTCCTTCCTCAGCCTCCCGAGTAGCTGGGATTGTAGGCGTGGGCCACCACACCCAGCTAATTTTTGTATTTTTAGTAGGGACAGGGTTTCACCATGTTGGCCTGGATGGTCTCGAACTCCTGACTTCTGACTCCAAGTGACCCACCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCGCCCAGCTGGCTTGGGATGGACTTTTTAAAAAGACACTCAGGTTTGGAATGTGGAGATCAGGAGCTCACCTTGTAAGACAAGCCACATTTCTGAGCTACCTCTTCCAGGTCTGCAGAAACCAGGTCCACCACTGAAAACAAAACACGTATAGCGGATTGGCAGAGAGGACTGGGGCCTCCCACACTTGGTTTTTCCTCATCTGTCAAATGGGGTGTCAATTCTACCCCCCGGCAGGCCGTCTCAGGAGGCCAGTGTGAAATAACAAAGCTGCAGGAGCCGGCGCGGTGCCCTGCACACAGTAGGAATCTCTACCCTGTTTTAGAGCTTGGCTCCCCACGCCCACCCTTCCTGAGCCTCTCCAGAAGCGCGGCCCTCTAGGAATGGAGGGGAAGCGCCCTGCAGGTATGCCAGGGCAGTGCGCCAGCCCTCGGGGCCTGCCCAGGTTGTGCGAGGCCCGCGCGGCTCCCTGGCACGCGCACACCCGGTCACCTGTCTTGATCCTGTGGCTCCTGAGAAGCTGGATCATCTCCTCGGTAAGGCCAGGGCACAGTCCGACCCTGAGCACGCCCATGTTCCCCGCAGGCCGGAACAGCCCCAGGGGGACTGCACGTCACGTGGGCATTCGCGGGGGGTCCTCTCCAGACGCCCCTCCCCTACCCCTTCCTAGAGAGGACACAGGCGCGCTGGCTGCCGGAGGAGAAAGGAGAGAGGAGGAGGCGGCACCAAGGGTAGGGCTGGGGGTCATCCGCCCGCCCGGGATCCGCCGGGATTCCCGCGCCCAGAGCCCGCCCGCCGGGTCGCGCCGCGCTGCCGCTTCCGGGTTCCAGGCTGGCGCGCGGCGAGGACCTGGCCTGCAGCGCCATCTGCGGGCCGCACGGGGCAGAGCCGCTGCGCCCCTCTCCACCGCCTGCACAGGTTCCCGAGTCCCACGACCCCCTCCGCGCTCAACACGCCACCCGCGGCCACATTCGGCCTCTACCTTCTGCCGCAACACACACACCGACCTTCTAAAGAGCCTTCTGTGCGCCAGCTTCCGTTCCAAACGGAACGGATCTCCGCTGGAGACAAAATGCGACACAAGACGACCCGCCCTTACCCCCAGGGAGCTTACTGTGAGCAAGGGAAAGACAGACAATGAAAAGGAATCGCAGAAATCACATCATTACAGATTATACGACAGGTGTCAAGAAGCAGCAAAGCATCCAGAGGGCACCTGCGTCTATTTTTCAAAAGTTTGTTTTGTTTTGGTTGAGACAGGGTCTCGATCGGCCGCCCAGGCTGGAGTGCCCTGGTGAGATCTCAGCTTTGCAGCCTCGACCTCCTGGGTTCAAGCGATCCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGTCACGTGCCACCTTGCCCAGCTAATTTTTGTATTTTTTGTAGAGGTTTCGCCTCTACAAAATGGGGTTACACCATGTTGCCCACACAGGTCTCGAACTACTGGGCTCAAACAATCCTCCTGCCTTGGTCTCCCGAAGTGCGGGGATTACAGGTGTGAGCCACCGTGCCCGGCCTCTATTTTTTATTTTATTTTTTATTTTTTTTAAGGGCAAGAAACCTTGGTTATATAGAACACACACAAAAAGATATGATTTGGTATTTTTAAATGTCCTTTGCTTTGCCTCATCCATAGGAAGAAATAAAACTTTACATGGTTATCTCATCACAAATCTGTGAGGGAGGCGCTATTTTTTATCCCTGTTTCACCAATGAAGAAACTGAGGTTCAGTGAGGTTAAATCACTTGCCAAAGGTCACCCAGCTAGGCGGCACAGGGCTGGACTTCACATCCACATCTGACTCTGCAAAGCCAGTGCTTTCTAACAGCCCCCCTCCCCACCCCTGAAGCTGTGTACATGTTTTCCTACTGTAAGGTGGTTTCTCTGAGAGCAGAGATCATGTGTGGCCCATCTCTGTATCCCACTGCAACTGCCACCATTGTCACTCCACACAGGAAAGTACTTGGGAGTGTGGGTGTGGCACATTTAGAATTCTAGCAGTGAAGTCTGATCATATGTGAGCCATGAACCCCTATGAACCATGTGGGCTTTCCCTTTCACTAACCGACTGGGCACAGTGGAGTCTGCAGCCTATGGTTTCAGGATAGAGAGCCTTAGCTTCTACGGACAAAGTTTCCCTCCCCAGCAGACACTTTCCAATACTGCCTATCTCTCAGGGCCACACCACCATCCTCTACATCCCACGCCCATCTCTCACCATCCTTATTCTCCTTCCCAGGGCAGTGCGGAAGGACACAGGTGTCAGGCATTTTGAGATCTTCAGAGAAGGGCAGGGCTGCCATCACCATGGAGTATTAGAGCTGGAAGGGGCCCAAGGGCTCATGCAGTCTGTTCCTTGGTTTTACCCCTCTCATGATGCTGCTTCACAGTCACACTGGCCCTTGGTCTGGCCAGCCACATAGCTAGCCTGGCAGCAGTAGCCTCAAATCAAGGGGGGAGGCTGGCCTGTAATTGTTACACTCTGTGATGATTATGAAGTCAGCTCATTGCACCTGCAGACTGTCCAAACTAAAGGTGGGCCACTGCCCCCACAGTTTCTCTCTGCTTCTGGTCAGCTGGGTTGTCCTGCATGGTGACGGGTGTCATCCCGAACAAATCAGATGGCATCAGAGGCACTCCATCAAGTGGGAGATGGGGAGGAGGCTGTACTGAAGAAAGAAAACTTCAACATGATGAATGCCCTTGACCAACTGCCAAAACCCTTTTCAAACCCCAAGTCTATGAACCGGACCGTCACTACCAAAGGACTCCCACTAGCCTCAAAGGGCAATTTGGTCAACTTCTTGGAGGATGATACCATCAACCTACTGTAAGTCACAAATCTGGTCCCTCCCTCCCTCCCTCCCTCCCTCCCTTCCTTCCTCCCTTCCTTCCTCCCTTCCTTCCTTCCTTCCTTTTTTTTTTTTTTTTTGACAGGATCTTGCTTTGTCACCCAGGCTGGAGTGCAGTGGTGCAATCTCGGCTCACTGCAGCCTTGAATTCTTGAGCTCAAGTGATCTTCCCACCTCCACCTCCCAAGTAGCTGGGACTATTGACGCGCCACCACCACACCTGGCTAATTTTCATATATATATATATATATATATATATATATATATATATATATATATATATAAATTTTTTTTTTTGGTAGAAACGGGGTTTCACCGTGTTGCCCAGGCTGGTCTTGAACTTCCGGGCTCAAGCGATCCTCCCGCCTCAGCCTCCCACAGTGTTGGGATTATAGGCTTGAGCCACCATGCCTATAGTTTCTAAGAAAGGCTGGAGCCGAGGGCTGGGCAGAGAGACAAAGAATCTATACTTCCCTGACTTGTCACAACCCAGTTCCTTGACTCCCAGAGAAGAGCGTGTGGGCAGGTTGGATCTATTTATGTATTCCTGAGCCCCAAATCACTTCTTGGAGGCATATGGAGCTCCCACTCCAGGAGGCCTTCTTGGATTAGTCAGTTTGTTGACAGTGCTCCTTATCCTGCCTTGACTGGCTGTGGTCCTCACCATCACCAAATCCCTGACACACCCATGGCTCCTCTTCCTCAACCCTCTCTCTTTGGTACCTTCATCTACCTGACTGCTCCCCAGTAGCCTGCCTTCCTTCGGACTGGGTTTTGCTGTTCCTCCTCACCAAGTCTGGTTTTCCTCTACTTCATTCCACAAAACTCTTTGAGCACCTGCAAGGTGTCTGTCCCAGTGTTTAAGTTCTGGGAACGCAGAGCTGGAAAGCACAGTCCCTGCCTTTAAGGAGCTCCCAGTCTGGCATGTGGAGGTCAGGGGTGAAAGGATGGGGATCATGCAATAACCAGAATGATATAGCATGGTCTGGTAAGTGCCAGGACAGGATGCCTTGAGGGACCAGAGGGGCTTAGTATAGCTTGAGACTGGGTGCAGTTGAAGGAGGCTTCTTGGAGGAAGTGATATTTGAGCTGAGTCTCCAAGGAAGGAAAGGAGTTAGCCAGTGAAGGGGTGGTGGTACAGGGTGATGTGGGCTGAGGGAATTACTTGCAGGTCACCCACCACATGGGTGAATGACCTGTGCAGTCACAAATAGCCCTGCACTTACAAGGGGCCTGTGCTTAGTTTAATGCTTTTCTGTTACTATCTTCAAATTCAGAATTTTTGAATAAGGGGCTCAGGGTACTTCAATTTGCACTGGGCTCCACAGACTACATAGCTGGTCTTGAGTATGTGAGAGGGATGTGGTGTCCATTCCCCAAAGTGCCCGTAAGCAAGCAGGTATGGCTAAAGTGATGGATGCTCGTAGGAAACTTCATGGTATACTGGGAATCTTGGACTAGAAGCCCAAACTCAGATCCAAGTTCTGCCACTTAGAGATTTATGGTCTTAGACAACTTAATTAAGATCGGAGGCCAGATGGGGTAGCCCACGCCTGTAATCCCAGCACTTTGAGAGGCTGAGGCGGATGCATCACTTGAAGTCAGGAGTTTGAGACCAGCCTGGCCAACATGGTGAAACCTCGTCTCTACTAAAAATACAAAAATTAGCTGGATGTGGTGGCACGCACCTGTTGTCCCAGCTACTCAAGAGGCTGAGGCGGAAGAATCCTTTGAACCTGGGAGGTGGAGGTCGCAGTGAGCCAAGATTGTGCCACTGCACTCCAGCCAGGGGTCTGGGAGACAGAGCAAGGCTCCATAAAAAAAACAAAACAAAACAAAAAAAAAAACAGATCAGGGACCCTCAGCCCCTTGTTTGCCAAATGGGGCTAACATCCATCCAGCAGAGCTGTTGTGAACATCAGGAGGAGGAGATGTTCAGCATGTAGCCAGTGCCTAGCGGCCTTCTGTGCTTGCTTCAGTACCAGCATTTGCAGTAAGTGAATCTGAAATATTAATTCATTAGGACAATCTAAAGCACATATGACATTAATACCCAGACTCTTCAGTCTACAAAAGACCTTGGTGGGGGAATCATTTATTCCAAATGTCCACCAAGCGCTAGCATAGGGGATCTGGGCTAATCAGGATTTCTCAGGAGGAGGCTGATGAGGCTGGAACCTGGGGAGGAAAAACTTGGCCCGTTCATCAACCAAGACCTGGGAGGCTGGATGGGAGTAAGGGATCCACAAACTGTGGATTGTGACCTATTAATGGGTCAAGAAGTCCTTCTAGTTGGTGAAGACCACTATGATAAAAATAAACTGGCTGGGTGCAGTGGCTCACGCCTGTAATCCTAGCACTTTGGAAGGCCAAGGCGGGCAGACCACGAGGTCAAGAGATCGAGACCATCCTGGCCAACATGGTGAAACCCCTTCTCTACTAAAAATACAAAAATTAGCTGAACATGGTGGC