LMNA NM_170707.4(LMNA):c.811-13T>A

CI-VAR-00008754Explore in graph →NM_170707.4:c.811-13T>AClinVar 48086 rs80356809

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
48086	Benign/Likely benign	criteria provided, multiple submitters, no conflicts	2	Lethal tight skin contracture syndrome; Lipoatrophy with Diabetes, Hepatic Steatosis, Hypertrophic Cardiomyopathy, and Leukomelanodermic Papules; Charcot-Marie-Tooth disease type 2B1; Mandibuloacral dysplasia with type A lipodystrophy; Congenital muscular dystrophy due to LMNA mutation; Emery-Dreifuss muscular dystrophy; Familial partial lipodystrophy, Dunnigan type; Dilated cardiomyopathy 1A; Cardiomyopathy; Emery-Dreifuss muscular dystrophy 2, autosomal dominant; Charcot-Marie-Tooth disease; Charcot-Marie-Tooth disease type 2; Cardiovascular phenotype; Familial pancreatic carcinoma; Melanoma; Lung cancer; Cervical cancer; Familial cancer of breast; Thyroid cancer, nonmedullary, 1; Malignant tumor of esophagus	germline	21	Jun 01, 2026	clinvar