Variant · Snv
PREPL NM_001171613.2(PREPL):c.-49+1813A>T
CI-VAR-00072842Explore in graph →NM_001171613.2:c.-49+1813A>TClinVar 478307 rs78349078
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-06
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260908-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 478307 | Benign | criteria provided, single submitter | 1 | Myasthenic syndrome, congenital, 22; Thyroid cancer, nonmedullary, 1; Acute myeloid leukemia; Uterine corpus endometrial carcinoma; Clear cell carcinoma of kidney; Sarcoma; Ovarian serous cystadenocarcinoma; Melanoma; Hepatocellular carcinoma | germline | 2 | Jan 27, 2026 | clinvar |