Variant · Snv
PIGT NM_015937.6(PIGT):c.533G>A (p.Arg178Gln)
CI-VAR-00080977Explore in graph →p.Arg178GlnNM_015937.6:c.533G>AClinVar 474456 rs80158178
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 474456 | Benign | criteria provided, multiple submitters, no conflicts | 2 | Multiple congenital anomalies-hypotonia-seizures syndrome 3; Uveal melanoma; Colorectal cancer; Sarcoma; Gastric cancer; Ovarian serous cystadenocarcinoma; Thyroid cancer, nonmedullary, 1; Malignant tumor of urinary bladder; Melanoma; Hepatocellular carcinoma; Nonpapillary renal cell carcinoma; Adrenocortical carcinoma, hereditary; Cervical cancer; Familial cancer of breast | germline | 5 | Feb 01, 2026 | clinvar |