TERT NM_198253.3(TERT):c.838G>A (p.Glu280Lys)

CI-VAR-00074576Explore in graph →p.Glu280LysNM_198253.3:c.838G>AClinVar 471904 rs199701877

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
471904	Conflicting classifications of pathogenicity	criteria provided, conflicting classifications	1	Interstitial lung disease 2; Dyskeratosis congenita; Idiopathic Pulmonary Fibrosis; Dyskeratosis congenita, autosomal dominant 2; Acute myeloid leukemia; Pulmonary fibrosis and/or bone marrow failure, Telomere-related, 1; Melanoma, cutaneous malignant, susceptibility to, 9	germline	12	Apr 06, 2026	clinvar