Variant · Snv
MAP3K1 NM_005921.2(MAP3K1):c.764A>G (p.Asn255Ser)
CI-VAR-00074612Explore in graph →p.Asn255SerNM_005921.2:c.764A>GClinVar 471695 rs56069227
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 471695 | Benign | criteria provided, multiple submitters, no conflicts | 2 | 46,XY sex reversal 6; Uterine corpus endometrial carcinoma; Colon adenocarcinoma; Sarcoma; Malignant tumor of esophagus; Colorectal cancer; Gastric cancer; Hepatocellular carcinoma; Cervical cancer; Thymoma; Thyroid cancer, nonmedullary, 1; Melanoma; Acute myeloid leukemia | germline | 6 | Feb 03, 2026 | clinvar |