TTN NM_001267550.2(TTN):c.21044C>T (p.Ala7015Val)

CI-VAR-00008723Explore in graph →p.Ala7015ValNM_001267550.2:c.21044C>TClinVar 46680 rs72648960

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
46680	Benign/Likely benign	criteria provided, multiple submitters, no conflicts	2	Cardiovascular phenotype; Myopathy, myofibrillar, 9, with early respiratory failure; Tibial muscular dystrophy; Early-onset myopathy with fatal cardiomyopathy; Autosomal recessive limb-girdle muscular dystrophy type 2J; Dilated cardiomyopathy 1G; Cardiomyopathy; Colon adenocarcinoma; Ovarian serous cystadenocarcinoma; Malignant tumor of esophagus	germline	21	Feb 03, 2026	clinvar