TTN NM_001267550.2(TTN):c.17048A>G (p.Tyr5683Cys)

CI-VAR-00008721Explore in graph →p.Tyr5683CysNM_001267550.2:c.17048A>GClinVar 46621 rs72648942

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
46621	Conflicting classifications of pathogenicity	criteria provided, conflicting classifications	1	Cardiovascular phenotype; Dilated cardiomyopathy 1G; Myopathy, myofibrillar, 9, with early respiratory failure; Tibial muscular dystrophy; Early-onset myopathy with fatal cardiomyopathy; Autosomal recessive limb-girdle muscular dystrophy type 2J; Cardiomyopathy; Brugada syndrome; TTN-related disorder; Sarcoma	germline	25	May 01, 2026	clinvar