PCDH15 NM_033056.4(PCDH15):c.5398G>A (p.Val1800Ile)

CI-VAR-00008717Explore in graph →p.Val1800IleNM_033056.4:c.5398G>AClinVar 46499 rs111033463

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
46499	Benign/Likely benign	criteria provided, multiple submitters, no conflicts	2	Usher syndrome type 1F; Usher syndrome type 1; Usher syndrome type 1D; Autosomal recessive nonsyndromic hearing loss 23; PCDH15-related disorder; Familial cancer of breast	germline	15	Jan 28, 2026	clinvar