SELENON NM_206926.2(SELENON):c.841G>A (p.Gly281Ser)

CI-VAR-00005410Explore in graph →p.Gly281SerNM_206926.2:c.841G>AClinVar 4496 rs121908188

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
4496	Pathogenic/Likely pathogenic	criteria provided, multiple submitters, no conflicts	2	Eichsfeld type congenital muscular dystrophy; Congenital myopathy with fiber type disproportion; SEPN1-related disorder; Congenital myopathy 4A, autosomal dominant; Malignant tumor of esophagus; Inborn genetic diseases; Desmin-related myopathy with Mallory body-like inclusions; SELENON-related disorder	germline	30	Jan 25, 2026	clinvar