UPB1 NM_016327.3(UPB1):c.917-1G>A

CI-VAR-00071697Explore in graph →NM_016327.3:c.917-1G>AClinVar 445946 rs143493067

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
445946	Pathogenic/Likely pathogenic	criteria provided, multiple submitters, no conflicts	2	Deficiency of beta-ureidopropionase; Inborn genetic diseases; UPB1-related disorder; Clear cell carcinoma of kidney; Cervical cancer; Malignant tumor of esophagus	germline	24	Jan 19, 2026	clinvar