PGAP1 NM_024989.4(PGAP1):c.1753C>G (p.Gln585Glu)

CI-VAR-00070586Explore in graph →p.Gln585GluNM_024989.4:c.1753C>GClinVar 436291 rs62185645

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
436291	Benign/Likely benign	criteria provided, multiple submitters, no conflicts	2	Intellectual disability, autosomal recessive 42; Hereditary spastic paraplegia; Thyroid cancer, nonmedullary, 1; Acute myeloid leukemia; Lung cancer; Cervical cancer; Gastric cancer	germline	9	Apr 01, 2026	clinvar