SIGMAR1 NM_005866.4(SIGMAR1):c.353-2A>G

CI-VAR-00395585Explore in graph →NM_005866.4:c.353-2A>GClinVar 4356097

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
4356097	Likely pathogenic	criteria provided, single submitter	1	Nonpapillary renal cell carcinoma; Amyotrophic lateral sclerosis type 16; Autosomal recessive distal spinal muscular atrophy 2	germline	2	Oct 04, 2025	clinvar