RTEL1 NM_001283009.1(RTEL1):c.3791G>A (p.Arg1264His)

CI-VAR-00008460Explore in graph →p.Arg1264HisNM_001283009.1:c.3791G>AClinVar 42018 rs201540674

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
42018	Pathogenic/Likely pathogenic	criteria provided, multiple submitters, no conflicts	2	Dyskeratosis congenita, autosomal recessive 5; Interstitial lung disease 2; Dyskeratosis congenita; Pulmonary fibrosis and/or bone marrow failure, Telomere-related, 3; Inborn genetic diseases; RTEL1-related disorder	germline	18	Feb 04, 2026	clinvar