Variant · Snv
MET NM_000245.4(MET):c.967A>G (p.Ser323Gly)
CI-VAR-00008233Explore in graph →p.Ser323GlyNM_000245.4:c.967A>GClinVar 41630 rs201467281
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-24
- Retrieved
- Sep 29, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260929-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 41630 | Conflicting classifications of pathogenicity | criteria provided, conflicting classifications | 1 | Papillary renal cell carcinoma type 1; Hereditary cancer-predisposing syndrome; Renal cell carcinoma; MET-related disorder; Hepatocellular carcinoma; Autosomal recessive nonsyndromic hearing loss 97; Osteofibrous dysplasia; Arthrogryposis, distal, IIa 11 | germline | 14 | Feb 01, 2026 | clinvar |