WT1 NM_024426.6(WT1):c.1269G>A (p.Glu423=)

CI-VAR-00062183Explore in graph →p.Glu423=NM_024426.6:c.1269G>AClinVar 414087 rs767850636

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
414087	Likely benign	criteria provided, multiple submitters, no conflicts	2	Wilms tumor 1; Frasier syndrome; Drash syndrome; 11p partial monosomy syndrome; Hereditary cancer-predisposing syndrome; Inborn genetic diseases	germline	5	Nov 04, 2025	clinvar