SDHAF2 NM_017841.4(SDHAF2):c.7G>T (p.Val3Leu)

CI-VAR-00062555Explore in graph →p.Val3LeuNM_017841.4:c.7G>TClinVar 411607 rs149277592

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
411607	Conflicting classifications of pathogenicity	criteria provided, conflicting classifications	1	Hereditary pheochromocytoma and paraganglioma; Hereditary cancer-predisposing syndrome; SDHAF2-related disorder; Pheochromocytoma/paraganglioma syndrome 2	germline	11	Jan 28, 2026	clinvar