Variant · Snv
PCCA NM_000282.4(PCCA):c.1651G>T (p.Val551Phe)
CI-VAR-00007840Explore in graph →p.Val551PheNM_000282.4:c.1651G>TClinVar 38865 rs61749895
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 38865 | Conflicting classifications of pathogenicity | criteria provided, conflicting classifications | 1 | Propionic acidemia; Ovarian serous cystadenocarcinoma; Thymoma; Nonpapillary renal cell carcinoma; Lung cancer; Clear cell carcinoma of kidney; Uveal melanoma; Colorectal cancer; Gastric cancer; Uterine carcinosarcoma; Adrenocortical carcinoma, hereditary; Cervical cancer; Thyroid cancer, nonmedullary, 1; Melanoma; Hepatocellular carcinoma; Malignant tumor of esophagus | germline | 11 | Jun 01, 2026 | clinvar |