PNPLA6 NM_001166114.2(PNPLA6):c.1252+17C>A

CI-VAR-00058006Explore in graph →NM_001166114.2:c.1252+17C>AClinVar 385065 rs117630756

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
385065	Benign	criteria provided, multiple submitters, no conflicts	2	Hereditary spastic paraplegia 39; Malignant lymphoma, large B-cell, diffuse; Sarcoma; Gastric cancer; Ovarian serous cystadenocarcinoma; Uterine carcinosarcoma; Thymoma; Malignant tumor of esophagus; Uveal melanoma; Acute myeloid leukemia	germline	4	Feb 02, 2026	clinvar