Variant · Snv
PDLIM3 NM_014476.6(PDLIM3):c.246G>A (p.Arg82=)
CI-VAR-00056508Explore in graph →p.Arg82=NM_014476.6:c.246G>AClinVar 380756 rs200354645
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-06
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260908-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 380756 | Conflicting classifications of pathogenicity | criteria provided, conflicting classifications | 1 | Hypertrophic cardiomyopathy; Primary dilated cardiomyopathy; Melanoma | germline | 6 | Sep 15, 2025 | clinvar |