STK11 NM_000455.4(STK11):c.-1115-328_-711del733

CI-VAR-00379684Explore in graph →NM_000455.4:c.-1115-328_-711del733ClinVar 3802394

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
3802394	Uncertain significance	criteria provided, single submitter	1	Hereditary cancer-predisposing syndrome	germline	1	Jan 23, 2025	clinvar

Nomenclature

Record

Gene: STK11
Type: Deletion
HGVS c.: NM_000455.4:c.-1115-328_-711del733
Assembly: GRCh38
Position: chr19:1205470-1206203
Ref / Alt: TTCCCGAGCCCCACCGAGGTCACAGCCGTGGCCTCGTCTCCCCATGCCTGCTTCCCGCCCCCTGCCCGTGACGGGCGTCTCCGAGGACCAATGAGCGCGCTGTATCCACCCCTCGGGCGGGGCCAAGCGCCGACCAATCGCCGCTCGGGCGCCCGGCCGGGTCCAAACGCTCCAATCGTCAGCGGCGGCGGGGCGGGCAGAGGGCCGGGGATGGCAGGTTCAACCAACGGGTGGGCACGTCGTCCTCGCGAGGAGGCGTGCCCTGCGGCCGGGCGTGCGGTGTCCGCGGCGGCGCAGGGAGGGGGAGGGAGGTAAACAAGATGGCGGCGGCGTGTCGGGCGCGGAAGGGGGAGGCGGCCCGGGGCGCCCGCGAGTGAGGCGCGGGGCGGCGAAGGGAGCGCGGGTGGCGGCACTTGCTGCCGCGGCCTTGGATGGGCTGGGCCCCCCTCGCCGCTCCGCCTCCTCCACACGCGCGGCGGCCGCGGCGAGGGGGACGCGCCGCCCGGGGCCCGGCACCTTCGGGAACCCCCCGGCCCGGAGCCTGCGGCCTGCGCCGCCTCGGCCGCCGGGAGCCCCGTGGAGCCCCCGCCGCCGCGCCGCCCCGCGGACCGGACGCTGAGGGCACTCGGGGCGGGGCGCGCGCTCGGGCAGACGTTTGCGGGGAGGGGGGCGCCTGCCGGGCCCCGGCGACCACCTTGGGGGTCGCGGGCCGGCTCGGGGGGCGCCCAGTGCGG → T

Per-assembly coordinates

stop
1206203
start
1205471
source
clinvar
assembly
GRCh38