Variant · Snv
IL2RG NM_000206.3(IL2RG):c.202G>A (p.Glu68Lys)
CI-VAR-00058437Explore in graph →p.Glu68LysNM_000206.3:c.202G>AClinVar 379561 rs1057520644
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-24
- Retrieved
- Sep 29, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260929-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 379561 | Pathogenic | reviewed by expert panel | 3 | X-linked severe combined immunodeficiency; Combined immunodeficiency, X-linked; Nonpapillary renal cell carcinoma; IL2RG-related disorders | germline | 7 | Jan 31, 2024 | clinvar |