TMEM132E NM_001304438.2(TMEM132E):c.-1174_-573dup

CI-VAR-00378269Explore in graph →NM_001304438.2:c.-1174_-573dupClinVar 3778950

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
3778950	Uncertain significance	criteria provided, single submitter	1	BRCA2-related cancer predisposition	germline	1	Mar 15, 2019	clinvar

Nomenclature

Record

Gene: TMEM132E
Type: Insertion
HGVS c.: NM_001304438.2:c.-1174_-573dup
Assembly: GRCh38
Position: chr17:34579902
Ref / Alt: G → GAGCGGGAGCCGATGCCCGGCAGCATCGAGACAGCGGGCGAACGGGCGTCCGGGGACAGGGTGGGGGCGGCGGGGAGGAGGCGTCGGAGACTCTGAACCCCAGAAAAGTTCAAGGTTTGTGCAGGTTCCCCCAGGGAAGGCGAGGAGCGAGGCGGGGCAGCGCGCCTCTCTGCCGAGACAGCGAGACCTTAGCGGGGTGGCCCGGAGCTGCCGTGAGCTGCAGGAGCCCCTCTGCATCTTACAGCGTTTATGGTCATCAAGCTGGAGTCGACGTCCTGGGCAGGAAGGGCTCGGGGCAGGGCGCATTAGCCGGCTTTCTCGCTCCCTCGCTTCTCCAAGCCCCATCTACATGGGGCAGCCCGTTCTGGCCGCGCCACCCTTGCCCCAGCCGCCGAGCGGCTGCCTGGGCAGGAGGCGCTGAGCCGGCCTGTGTGGAGCCTGGGCCCTGATCCAGACTGGAGAAAGCGCGCTGGAGCGGAGGAGCGAGCCTTGCGAGGGGACAAACATCTGGCCGCCCGCCTCGGGCATCCGGTCTGGGCGTCGCCTAGGGTGGTGGCGACCGGCGTCGCCAGTTTCAGCACCGCACGGAAACTTTTCCTTCTC

Per-assembly coordinates

stop
34579903
start
34579902
source
clinvar
assembly
GRCh38
chromosome